As per Washington state guidance, masks are required regardless of vaccination status in all of our facilities. Please be aware that if you do not have a mask when you arrive we can provide one for you or reschedule your appointment. Exposure to someone that has tested positive for COVID requires a 14 day wait time regardless of vaccination status or a negative test before being seen in person. We appreciate your understanding!


A Phase 2, Open Label Study to Evaluate Safety, Efficacy, and Pharmacokinetics of Induction Therapy with PRA023 in Subjects with Moderately to Severely Active Crohn's Disease.

PRA023 is a humanized IgG1k monoclonal antibody that binds human TL1A with high affinity and specificity. PRA023 is derived from the murine monoclonal antibody 5C3D11, which was discovered using conventional hybridoma technology. PRA023 consists of the 5C3D11 complementarity-determining regions (CDRs) grafted to human sequences from the IGHV1 and IGKV3 families. PRA023 incorporates Fc mutations to avoid ADCC and CDC.

  • Cannot have failed 3 or more classes or 4 or more individual biologic therapies
  • Must be on stable doses of Oral aminosalicylates and oral corticosteroids for 2 weeks (< 20mg prednisone or </= 9mg budesonide or Beclamethasone </= 5mg)
  • Randomized 1:1 to receive PRA023 250mg IV Q4W or 100mg IV Q4W until week
  • Subjects who do not respond by 12 weeks will be discontinued

If you are interested in participating in clinical studies, please send an email to

17 Locations Focused on Serving Your Needs

Email us at